2011年9月25日 星期日

Are the whitening effects of Glutathione permanent?




What is GLUTATHIONE (榖胱甘肽)

Glutathione, GSH, Gamma-L-glutamyl-L-cysteninylglycine: The Super Supplement of the Decade

Who wouldn’t like to have a naturally occurring substance that acts as a super antioxidant, an immune system booster, and a detoxifier? As a bonus, it will help your body repair damages caused by stress, pollution, radiation, infection, drugs, poor diet, aging, injury, trauma, and burns?

An army of advanced researchers are saying that glutathione can do all the above and maybe more. But can you believe such sweeping claims? What is the evidence to back them up? Here is what the experts have to say:

What is Glutathione?

Glutathione is a super antioxidant that is important for your good health because they neutralize “free radicals”, which can build up in cells and cause damage. Because glutathione exists within the cells, it is in a prime position to neutralize “free radicals”. It also has potentially widespread health benefits because it can be found in all types of cells, including the cells of the immune system, whose job is to fight disease.

What Does Glutathione Specialist do?
The strong antioxidant effect of glutathione helps keep cells running smoothly. Glutathione expert, Jeremy Appleton, ND, Chairman of the Department of Nutrition at the National College of Naturopathic Medicine, say it also helps the liver remove chemicals that are foreign to the body, such as drugs and pollutants.

“IF you look in a hospital situation at people who have cancer, AIDS, or other very serious disease, almost invariably they are depleted of glutathione,” says Dr. Appleton. “The reasons for this are not completely understood, but we do know that glutathione is extremely important for maintaining intracellular health.”

How should Glutathione be Taken?
Glutathione is not absorbed into the body when taken by mouth. One way to get around that is to take it by injection in the vein. Another way is to take amino acids precursors, that is, the molecules the body needs to make glutathione, but there is no solid proof this works and most doctors doubt its validity.

Glutathione Specialist is a New major breakthrough because it uses the latest technology of micro-encapsulating reduced glutathione, methylcobolamine B12, Folinic acid into phosphatidylcholine, an essential phospholipids that is natural to the cell and brain, called Glutathione Lyposome to deliver directly into the blood stream, even crossing the Brain Barrier in very high concentrations effectively and quickly.

Dr. Appleton says “Glutathione and other antioxidants, far from interfering with the activity of chemotherapy, appear to reduce side effects without decreasing efficacy and may, in fact, improve the efficacy of the chemotherapy in fighting cancer.”

Glutathione is also used to prevent oxidative stress in most cells and helps to trap and neutralize “free radicals” that can damage DNA and RNA. There is a direct correlation with the speed of aging and the reduction of glutathione concentrations in intracellular fluids. As individuals grow older, glutathione levels drop, and the ability to detoxify free radicals decreases.

Glutathione preliminary evidence that it might eventually prove to be useful in the management of some cancers, atherosclerosis, diabetes, lung disorders, noise-induced hearing loss, male infertility and to help prevent various heavy metal and chemical toxicities. Glutathione also has been researched for AIDS associated Cachexia, Cystic Fibrosis, Parkinsons, ADHD, Autism, Multiple Sclerosis, Cancer, Mercury poisoning, Lupus, ALS, and liver diseases.

A case history by Mr. Martin, a semi-retired researcher, experienced hands-on evidence of the power of raising his Glutathione level. For years, he suffered from Chronic Fatigue Syndrome and fibromyalgia that countless medical practitioners were not able to neither recognize nor treat. When he became so debilitated that he considered purchasing a walker or a wheel chair by his early 50s, he decided to take charge of his own health. After doing extensive research, then boosting his glutathione levels, he regained his mobility and natural high energy. "Within a week, I realized I didn't hurt anymore," says Mr. Martin. "I just got better and better. It was so simple and so astounding." He has never looked back. Today, he continues to maintain his glutathione level, which is vibrant and healthy, and he "rarely gets a cold."

Increased Glutathione levels have been researched in:
1. Detoxify the liver
2. Improve Lung Function
3. Improve Heart Function
4. Increased Energy, Endurance, and Stamina
5. Protect the Skin from UV sunlight
6. Strengthen Immune Function
7. Helping AIDS related symptoms
8. Multiple Sclerosis, Lupus, ALS.
9. ADHD & Autism
10. Cancer & Chemotherapy side effects
11. Alzheimer, Parkinson, and Memory Deficits
12. Diabetes & Sugar Metabolism
13. Cardio Vascular Disease & Athrosclerosis
14. Adrenal Fatigue & Fibromyalgia

Biochemistry and Metabolism:

Reduced Glutathione (GSH) is a linear tripeptide of L-glutamine, L-cysteine, and glycine. Technically N-L-gamma-glutamyl-cysteinyl glycine or L-Glutathione, the molecule has a sulfhydryl (SH) group on the cysteinyl portion, which accounts for its strong electron-donating character.

As electrons are lost, the molecule becomes oxidized, and two such molecules become linked (dimerized) by a disulfide bridge to form Glutathione disulfide or oxidized Glutathione (GSSG). This linkage is reversible upon re-reduction.

Glutathione is under tight homeostatic control both intracellularly and extracellularly. A dynamic balance is maintained between GSH synthesis, it’s recycling from GSSG/oxidized Glutathione, and its utilization.

Glutathione synthesis involves two closely linked, enzymatically-controlled reactions that utilize ATP. First, cysteine and glutamate are combined by gamma-glutamyl cysteinyl synthetase. Second, GSH synthetase combines gamma-glutamylcysteine with glycine to generate Glutathione. As Glutathione levels rise, they self-limit further GSH synthesis; otherwise, cysteine availability is usually rate-limiting. Fasting, protein-energy malnutrition, or other dietary amino acid deficiencies limit Glutathione synthesis.

Glutathione recycling is catalyzed by Glutathione disulfide reductase, which uses reducing equivalents from NADPH to reconvert GSSG to 2GSH. The reducing power of ascorbate helps conserve systemic Glutathione.

Glutathione is used as a cofactor by (1) multiple peroxidase enzymes, to detoxify peroxides generated from oxygen radical attack on biological molecules; (2) transhydrogenases, to reduce oxidized centers on DNA, proteins, and other biomolecules; and (3) Glutathione S-transferases (GST) to conjugate Gluathione with endogenous substances (e.g., estrogens), exogenous electrophiles (e.g., arene oxides, unsaturated carbonyls, organic halides), and diverse xenobiotics. Low GST activity may increase risk for disease—but paradoxically, some Glutathione conjugates can also be toxic.

Direct attack by free radicals and other oxidative agents can also deplete Glutathione. The homeostatic Glutathione redox cycle attempts to keep Glutathione repleted as it is being consumed. Amounts available from foods are limited (less that 150 mg/day), and oxidative depletion can outpace synthesis.

The liver is the largest Glutathione reservoir. The parenchymal cells synthesize GSH for P450 conjugation and numerous other metabolic requirements—then export GSH as a systemic source of SH-reducing power. Glutathione is carried in the bile to the intestinal luminal compartment. Epithelial tissues of the kidney tubules, intestinal lining and lung have substantial P450 activity—and modest capacity to export Glutathione.

Glutathione equivalents circulate in the blood predominantly as cystine, the oxidized and more stable form of cysteine. Cells import cystine from the blood, reconvert it to cysteine (likely using ascorbate as cofactor), and from it synthesize GSH. Conversely, inside the cell, Glutathione helps re-reduce oxidized forms of other antioxidants—such as ascorbate and alpha-tocopherol.

Mechanism of action

Glutathione is an extremely important cell protectant. It directly quenches reactive hydroxyl free radicals, other oxygen-centered free radicals, and radical centers on DNA and other biomolecules. Glutathione is a primary protectant of skin, lens, cornea, and retina against radiation damage and other biochemical foundations of P450 detoxification in the liver, kidneys, lungs, intestinal, epithelia and other organs.

Glutathione is the essential cofactor for many enzymes that require thiol-reducing equivalents, and helps keep redox-sensitive active sites on enzyme in the necessary reduced state. Higher-order thiol cell systems, the metallothioneins, thioredoxins and other redox regulator proteins are ultimately regulated by Glutathione levels—and the GSH/GSSG redox ratio. GSH/GSSG balance is crucial to homeostasis—stabilizing the cellular biomolecular spectrum, and facilitating cellular performance and survival.

Glutathione and its metabolites also interface with energetics and neurotransmitter syntheses through several prominent metabolic pathways. Glutathione availability down-regulates the pro-inflammatory potential of leukotrienes and other eicosanoids. Recently discovered S-nitroso metabolites, generated in vivo from Glutathione and NO (nitric oxide), further diversify Glutathione's impact on metabolism.


Hows Glutathione Works to Glow Your SKIN



This is the inner layer of the skin called Dermis and the outer surface which is visible in our eyes is the Epidermis. The primary determinant of variability in human skin color is the Melanin and Melanocyte is a cell that synthesizes it. L-glutathione,, starts the lightening process in the Dermis working its way out to the surface.



This is the point where the metabolic pathway of Melanin begins. As you see in the diagram GSH(Reduced Glutathione) intervenes the metabolism. There are certain kinds of compounds that inhibits the Tyrosinase Activity and L-glutathione is one of them.



The oral use of Reduced Glutathione(L-glutathione) inhibits the Tyrosinase Activity. Once it has been inhibited, the metabolic pathway then reverses its course going to the synthesis of light pigmented melanin called Phaeomelanin instead of synthesizing dark pigmented melanin called Eumelanin. The cycle continously flow as long as the presence of L-glutathione co-exist in the metabolic pathway of melanin. Finally, light skin will reveal to the surface gradually changing your complexion.



Are the whitening effects of Glutathione permanent? 
Will my skin tone go back to its original colour once you stop taking it?

Its whitening effects are permanent only if you will maintain it (by avoiding exposure to sunlight).
The reason why are skin becomes white in using L-Glutathione is because it reverses the dark melanin pigments turning to a light pigments and reduces melanocytes which produces melanin. Less melanin,a whiter skin. L-Glutathione's whitening process starts inside the skin (dermal layer) going outside (epidermal layer), that's the reason why it takes time to be able to see initial change in your skin tone. The whitening process is goes head to foot meaning that you will have a white even skin tone in your whole body. Glutathione is the latest whitening innovation greatly recommended bydermatologists and skin care specialists. It is considered to be the most powerful, most versatile, and most important of the body's self-generated antioxidants.
Suggested duration for usage:

If your skin is medium brown: take it for at least one to three months

If your skin is dark brown: take glutathione for at least three to six months

If your skin is dark: take it for six to 12 months

If your skin is very dark: may need L glutathione for at least two years or even more

Once a person has her desired skin colour: the maintenance dose can be 1 tab of 500mg-100mg once a day

It is advisable to still continue taking the pills even though you have achieved the skin tone you want. Take 1 capsule a day as maintenance. We all know that L-Glutathione is very good to our health and so taking it in long term will not only make us white but also it will promote better health.
Are the whitening effects of Glutathione permanent?
In taking care and maintaining something in our body, you must have a healthy habit and discipline to stay with the ideal effects that we want. Therefore, we must take 1 capsule a day for our maintenance and we should not expose ourselves from the harmful rays of sun.
Even though the sunlight was said that it provides vitamin D, everyone is aware of the depletion of the ozone layer, and anything that is over wouldn't have a better result in the body. In fact too much exposure will increases the melanin pigments in the skin, thus, might delay the whitening process. It's not really bad to be exposed to sunlight as long as we have protection such as sun block. Use sunblock or sunscreen lotion that has an SPF of 30-60. It will protect you from the harmful effects of the sun.
High dosage of Glutathione: Glutathione is water-soluble, meaning that if there would be an excessive amount of intake it would still be excreted through urine.
Unlike any other whitening pills / capsules, glutathione don't just concentrate on whitening of the skin itself, it is also an anti oxidant and anti aging pill which makes us healthy and stress free. No harmful effects on the body and is recommended by eminent dermatologist and doctors for people with liver problems.



This is the inner layer of the skin called dermis and the outer surface which is visible in our eyes is the epidermis. The primary determinant of variability in human skin color is the melanin and melanocyte is a cell that synthesizes it. L-glutathione, the whitening pill"s main component, starts the lightening process in the dermis working its way out to the surface.


http://www.consultdrminas.com/picture/pages/melanin.gif
This is the point where the metabolic pathway of melanin begins. As you see in the diagram GSH(reduced glutathione) intervenes the metabolism. There are certain kinds of compounds that inhibits the tyrosinase activity and L-glutathione is one of them.




Glutathione (GSH)

Forms/Synonyms:
Reduced L-glutathione

Chemical Name:
Gamma-L-glutamyl-L-cysteninylglycine.

Chemistry/Function:
L-Glutathione is a biologically active sulfur amino acid tripeptide compound containing three amino acids L-Cysteine, L-Glutamic Acid and Glycine. Most glutathione is found in the liver where it detoxifies many harmful compounds to be excreted thru the bile. Some glutathione can also be found in red and white blood cells, the lungs and the intestinal tract. The primary biological function of glutathione is to act as a non-enzymatic reducing agent to help keep cysteine thiol side chains in a reduced state on the surface of proteins. Reduced glutathione is involved in the synthesis and repair of DNA, helps to recycle vitamins C and E, blocks free radical damage and enhances the antioxidant activity of vitamin C, facilitates the transport of amino acids, and plays a critical role in the detoxification of harmful compounds. It is also the base material for several other key antioxidant enzyme systems including glutathione-peroxidase, glutathione-reductase, and glutathione-transferase. Declines in glutathione concentrations in intracellular fluids correlate directly with indicators of aging.

Dietary Sources:
Glutathione is derived from L-Cysteine, L-Glutamic Acid and Glycine and is not consumed directly as a food constituent. Glutathione levels are enhanced via intake of vitamin C.

Supplemental Sources:
A daily dose of 500 mg of vitamin C may be adequate to elevate and maintain reduced glutathione concentrations in the blood. In contrast, direct consumption of glutathione orally does not seem to be an effective means of enhancing liver and intracellular gltathione levels. Following a small human study with seven subjects Witschi et al concluded that "because of hydrolysis of glutathione by intestinal and hepatic gamma-glutamyltransferase, dietary glutathione is not a major determinant of circulating glutathione, and it is not possible to increase circulating glutathione to a clinically beneficial extent by the oral administration of a single dose of 3 g of glutathione". On the other hand, intravenous glutathione administration may provide a direct and effective route for increasing intracellualr glutathione levels. Evidence indicates that oral consumption of NAC (N-Acetyl-Cysteine) may be an effective, but not necessarily safe or efficient, means of enhancing glutathione levels.
(Johnston CS, et al. Am J Clin Nutr. 1993 Jul;58(1):103-105; Witschi A, et al. Eur J Clin Pharmacol. 1992;43(6):667-669.) 

Deficiency:
Symptoms of glutathione deficiency may include coordination problems, generalized cell damage, mental disorders, various nervous system disorders, tremors, and twitching. Red cells are prone to burst, white blood cells decline in function, and nerve tissue degenerates. A deficiency of intracellular glutathione has been associated with a variety of conditions including AIDS, alcohol-induced liver disease and some forms of cancer.

Proven or Potential Therapeutic Uses:
Antioxidant action, cancer, cataracts, liver disease, macular degeneration.

Mechanism:
Support of antidoxidant processes.

Maintenance Dose:
Usually not necessary. Optimal levels of intake have not been established. 50 mg is a common dose in supplemental forms.

Therapeutic Dose:
500 mg a day is used by some practitioners to treat various conditions.

Side Effects:
Glutathione is generally considered to be free of side effects.

Toxicity:
No toxicities have been reported or suspected as being associated with glutathione.

Contraindications:
None known, except for use during some forms of chemotherapy and radiation where antioxidants are contraindicated due to their inhibition of the free radical formation which is an intentional part of the therapeutic mechanism. 



Eumelanin- and pheomelanin-based colour advertise resistance to oxidative stress in opposite ways.
J Evol Biol. 2011 Oct;24(10):2241-7. doi: 10.1111/j.1420-9101.2011.02353.x. Epub 2011 Jul 11.
Roulin A, Almasi B, Meichtry-Stier KS, Jenni L.
Source
Department of Ecology & Evolution, University of Lausanne, Lausanne, Switzerland Swiss Ornithological Institute, Sempach, Switzerland.
Abstract
The control mechanisms and information content of melanin-based colourations are still debated among evolutionary biologists. Recent hypotheses contend that molecules involved in melanogenesis alter other physiological processes, thereby generating covariation between melanin-based colouration and other phenotypic attributes. Interestingly, several molecules such as agouti and glutathione that trigger the production of reddish-brown pheomelanin have an inhibitory effect on the production of black/grey eumelanin, whereas other hormones, such as melanocortins, have the opposite effect. We therefore propose the hypothesis that phenotypic traits positively correlated with the degree of eumelanin-based colouration may be negatively correlated with the degree of pheomelanin-based colouration, or vice versa. Given the role played by the melanocortin system and glutathione on melanogenesis and resistance to oxidative stress, we examined the prediction that resistance to oxidative stress is positively correlated with the degree of black colouration but negatively with the degree of reddish colouration. Using the barn owl (Tyto alba) as a model organism, we swapped eggs between randomly chosen nests to allocate genotypes randomly among environments and then we measured resistance to oxidative stress using the KRL assay in nestlings raised by foster parents. As predicted, the degree of black and reddish pigmentations was positively and negatively correlated, respectively, with resistance to oxidative stress. Our results reveal that eumelanin- and pheomelanin-based colourations can be redundant signals of resistance to oxidative stress.



Glutathione plays a key role in the depigmenting and melanocytotoxic action of N-acetyl-4-S-cysteaminylphenol in black and yellow hair follicles.
J Invest Dermatol. 1995 May;104(5):792-7.
Alena F, Dixon W, Thomas P, Jimbow K.
Faculty of Medicine, University of Alberta, Edmonton, Canada
Abstract
This study examined the effect of glutathione on the in vivo depigmenting potency of N-acetyl-4-S-cysteaminylphenol (N-acetyl-4-S-CAP) in black and yellow mice after multiple intraperitoneal injections on 10 consecutive days. In black mice (C57BL/6J, a/a), N-acetyl-4-S-CAP showed dose-dependent depigmenting potency (0.5, 1.0, and 2.0 mmol/kg), which was in parallel to the tissue eumelanin content (98%, 28%, and 3% of controls, respectively) and to the tissue glutathione content (94%, 85%, and 76%, respectively). In lethal yellow mice (C57BL/6J, Ay/a), only a dose of 2.0 mmol/kg showed the color change of hair to dark, not to white as seen in black mice. This was reflected by the decrease of pheomelanin content (56%) and the increase of eumelanin content (28% of black mice). The simultaneous administration of N-acetyl-cysteine, which up-regulated glutathione content, completely abolished the depigmenting potency of N-acetyl-4-S-CAP, whereas administration of buthionine sulfoximine, which depleted the tissue glutathione content, enhanced the depigmenting potency of N-acetyl-4-S-CAP in black hair. In yellow mice, the darkening of hair follicles by 2.0 mmol/kg of N-acetyl-4-S-CAP was completely abolished by the combined administration of N-acetyl-cysteine, with the resulting hair color the same as in controls, whereas combined administration with buthionine sulfoximine caused some whitening of yellow hair follicles. Our data indicate that the tissue content of glutathione regulates melanocytotoxicity and depigmenting potency of N-acetyl-4-S-CAP and that this alteration of glutathione content may switch the melanogenesis type from pheomelanin to eumelanin.



know more about Glutathione.....





Is Glutathione good for skin whitening? If so how? Any claims?

glutathione is a very good anti-oxidant, and a very effective whitening if you will take it on a greater dosage.

1.  is an anti-oxidant that cleans the liver, takes off free-radicals and helps the brain too (did u know that our brain's anti-oxidant is gluta and that low level of it results to some illneses and disorders?)

2. gluta is safe for everyone whatever age is

3. the most advisable dosage is 10-20mg/kg BodyWeight to use glutathione as an anti-oxidant and for whitening it has to be 20-40mg/kg/BW. example: 50kg x 20mg = 1000mg. you have to take it with vitamin c in ascorbic acid form to be able to maximize its whitening effect (vitamin e can also be taken for better results although i don’t really encourage you to do so because ive learned that there are forms of vitamin e which are not water-soluble and it may harm our body in prolonged use). it means that you are just taking dosage of glutathione as an anti-oxidant and not as skin whitener (because i assume that all in all, you are taking 400 mg of )

4. it is 100 percent proven that it really works to whiten skin

5. For most people, the first 3 months use of gluta (fortunately for me, this happened for only 2 mts) is crucial for it is the time where gluta is building the foundation (body chemistry re-alignment) and once built this is only the start for its whitening process. the lightening of skin is gradual (speed is depending on your metabolism and body chemical functioning) this is where you will notice that your skin is shinier and healthier than before. after this process, you will notice that your shade is lighter than before.

6. glutha whitens the skin by reducing the melanin formation of the epidermis going up to the dermis

7. there are definitely no side-effects of using gluta, u know why? coz its ability to whiten your skin is already its side-effect

8. there is also no harm in its prolonged use

9. its advisable to take gluta with meal and never take it with liquor or any alcoholic drink

10. while taking this, you wont really become sensitive but you have to at least put sunblock lotion or cream to exposed parts of your body and your face.
http://www.askmehelpdesk.com/skin-lighte…


For skin lightening, avoid products with HYDROQUINONE

Other things to help
Licorice extract 

magnesium ascorbyl phosphate
http://www.emedicine.com/derm/topic528.h…

Lemon Juice

Rosehip Oil
Is glutathione good for skin whitening? if so how? any claims? - Yahoo! Answers


Glutathione Skin Whitening – Does it Really Whiten Skin?

Glutathione whitening skin is one of skin whitening remedy that is really help whiten our skin. It  have been proved and there is many testimonial about glutathione whitening skin works. It is safe for everyone no matter there age.
Glutathione skin whitening is proved very effective on whitening skin. Beside that it is also an anti-oxidant, anti-acne and anti-aging. But don’t put your hope to high, it is like other skin whitening product, it takes time for showing the result.
Glutathione whitening skin works by decreasing the proces speed on melanin getting up to the epidermis, which slow down the skin pigmentation speed. And finally whiten our skin.

How long it Takes for Glutathione Skin Whitening?

Glutathione skin whitening speed is vary on different person. On brown skin it takes about 2 month to show result, and for darker skin it may takes longer.

Is taking Glutathione Skin Whitening Dangerous?

No, of course not. Because glutathione is naturally made from our body. It is made by amino acids: amino acids, glutamic acid, cysteine and glycine.
Here are list, where does glutathione come from:
  • grapefruits
  • tomatoes
  • carrots
  • avocado
  • asparagus
  • apples
  • spinach
Glutathione skin whitening is 100% safe to use. Because it is not a drugs, but it is a food supplement.
Glutathione skin whitening is an adverse nitrogen stability brought on by bodily overtraining, most cancers, sepsis, HELPS, uses up as well as stress is actually related to reduced glutathione content material in your body. Prior research display which HELPS sufferers demonstrated a greater price associated with success whenever provided the best dose associated with glutathione.
Research display from glutathione skin whitening which oxidative tension can be a main element in the actual occurrence associated with depressive disorders, schizophrenia as well as bipolar illness. Because glutathione is actually thought to be the actual main free of charge revolutionary scavenger within the mind, a higher glutathione content material within the mind is actually thought to considerably reduce the actual occurrence of those 3 devastating illnesses.
Several France scientists discovered which supplement Deb encourages glutathione manufacturing bringing on elevated glutathione amounts within the mind. Supplement D3 or even cholecalciferol may be the Deb supplement that’s particularly related to this particular trend acquired possibly with the diet plan or even through contact with the actual sunshine. Which means that glutathione manufacturing in your body is actually elevated if you take supplement D3 dietary supplements as well as through contact with sunshine.
Glutathione skin whitening content material within the lean meats as well as plasma could be elevated if you take health supplements which function because precursors in order to glutathione manufacturing for example n-aceytl-cysteine, S-adenosylmethionine (Exact same) as well as whey proteins.
Additional dietary supplements recognized to improve glutathione manufacturing tend to be leader lipoic acidity that accounts for replenishing glutathione within the tissue, melatonin with regard to revitalizing the actual enzyme, glutathione peroxidase as well as silymarin, from whole milk thistle seedling draw out.
It is safe, so just try glutathione skin whitening.


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Glutathione is now one of the most talked about beauty supplement in Asia. Used by most celebrities, it is now very popular to dark-skinned people of Asians and African descent. Men and women, who want to have whiter skin and look younger, are now taking Glutathione. People who are health conscious are also using this supplement because of its various significant health benefits. These days, beauty is essential, beauty is a must. Beauty is a treasure you cant keep forever, but now, with BeauOxi White Plus 5in1, you can keep it longer than you can imagine. Give value to yourself and to your health.
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44 則留言:

  1. Hi this one is great and is really a good post. I think it will help me a lot in the related stuff and is very much useful for me. Very well written I appreciate & must say good job..
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  2. Nice blog!!
    Thanks for explaining the effects of Glutathione is permanent or not and how to get permanent results by using Glutathione

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  3. Skin Whitening Treatment
    Many treatments use a combination of topical lotions or gels along with a sunscreen. Skin Whitening Treatment

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  4. Skin lightening surgery is an option to using of expensive whitening creams that lightens the skin.What is cost of this treatment in India,let me know pls.

    Ashmita

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  5. Hi. I would recommend Dermalmd Skin Lighter serum as a skin brightener and moisturizer. It can be used on the body as well. If your legs are really dry you might try using products with oils in them.

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  6. Hi,
    There are various Skin Whitening Injections and those who have dark complexion can have them to lighten their skin tone. Glutathione skin whitening treatment is the most effective and safe treatment for dark skin tone. This treatment involves the use of detoxification injections to lighten the skin tone.

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  7. Hi,
    There are various skin whitening treatments and those who have dark complexion can have them to lighten their skin tone. Glutathione skin whitening treatment is the most effective and safe treatment for dark skin tone. This treatment involves the use of detoxification injections to lighten the skin tone. These injections contain the vitamin C and glutathione that is a natural enzyme which helps break down the body toxins.
    Skin Whitening Injections

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  8. Such a nice and wonderful tips you have shared here with us for skin whitening. Really very useful and informative blog . If you want to know more about Skin Whitening Treatment visit Skin Lightening Treatment in Dubai

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  9. Glutathione is a super antioxidant that is important for your good health because they neutralize “free radicals”, which can build up in cells and cause damage. Bionova provides products of Glutathione tablets.This tablets maintaining in our body.

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  10. We are also provide the Best injections of skin whitening its name is glutathione its work so quickly and had also fabolous results further info visit on Glutathione injections in Dubai

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  11. Skin whitening injections can also help in removing of the skin lines and wrinkle. Whitening injection treatment cost is very much affordable and also very effective too in India.

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  12. hai, interested with glutathione products? visit www.beautyworldinspiration.com

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